Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Respiratory failure
ADR ID BADD_A03813
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.04      Respiratory acidoses
14.01.04.003      Respiratory failure
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.06      Respiratory failures (excl neonatal)
22.02.06.002      Respiratory failure
Description A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. [CTCAE] Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code 10038695
MeSH ID D012131; D012131; D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Failure respiratory | Other pulmonary insufficiency, not elsewhere classified | Pulmonary insufficiency following trauma and surgery | Respiration failure | Respiratory failure | Respiratory failure (excl neonatal) | Respiratory insufficiency | Ventilatory failure | Pulmonary failure | Hypercapnic respiratory failure | Restrictive respiratory insufficiency | Respiratory failure aggravated | Hypoxic respiratory failure | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01242Lamivudine0.018551%
BADD_D01243Lamotrigine0.000908%
BADD_D01245Lansoprazole0.000437%
BADD_D01248Lapatinib--
BADD_D01249Laronidase--
BADD_D01252Leflunomide0.002155%
BADD_D01253Lenalidomide--
BADD_D01254Lenvatinib--
BADD_D01257Letrozole--
BADD_D01258Leucovorin0.005324%
BADD_D01265Levetiracetam--
BADD_D01267Levobunolol--
BADD_D01268Levobunolol hydrochloride--
BADD_D01269Levobupivacaine--
BADD_D01275Levofloxacin--
BADD_D01281Levonorgestrel--
BADD_D01282Levorphanol--
BADD_D01285Levothyroxine--
BADD_D01288Lidocaine hydrochloride--
BADD_D01295Linezolid0.014765%
BADD_D01300Lisinopril0.000109%
BADD_D01303Lithium carbonate0.000960%
BADD_D01318Lorazepam0.000438%
BADD_D01322Losartan--
BADD_D01328Lubiprostone0.000509%
BADD_D01336Macitentan0.009112%
BADD_D01352Maraviroc--
BADD_D01374Meloxicam--
BADD_D01376Melphalan0.000347%
BADD_D01378Memantine0.000451%
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